Rafael S. Depetris, Ph.D.

Affiliations: 
2008 Basic Medical Science New York University, New York, NY, United States 
Area:
Molecular Biology
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"Rafael Depetris"

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Stevan Hubbard grad student 2008 NYU
 (Structural and functional studies of the interaction of Grb14 and Grb10 with the insulin receptor.)
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Publications

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Depetris RS, Lu D, Polonskaya Z, et al. (2021) Functional antibody characterization via direct structural analysis and information-driven protein-protein docking. Proteins
Klasse PJ, Depetris RS, Pejchal R, et al. (2013) Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein. Journal of Virology. 87: 9873-85
Julien JP, Sok D, Khayat R, et al. (2013) Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathogens. 9: e1003342
Depetris RS, Julien JP, Khayat R, et al. (2012) Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. The Journal of Biological Chemistry. 287: 24239-54
Julien J, Kong L, Pejchal R, et al. (2012) Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies Retrovirology. 9: P48
Pejchal R, Doores KJ, Walker LM, et al. (2011) A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103
Harris A, Borgnia MJ, Shi D, et al. (2011) Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Proceedings of the National Academy of Sciences of the United States of America. 108: 11440-11445
Anastassopoulou CG, Ketas TJ, Depetris RS, et al. (2011) Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41. Virology. 413: 47-59
Depetris RS, Wu J, Hubbard SR. (2009) Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14. Nature Structural & Molecular Biology. 16: 833-9
Li S, Depetris RS, Barford D, et al. (2005) Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase. Structure (London, England : 1993). 13: 1643-51
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