Jason M. Singer, Ph.D.
Affiliations: | 2004 | University of Utah, Salt Lake City, UT |
Area:
Cell Biology, GeneticsGoogle:
"Jason Singer"Parents
Sign in to add mentor| Janet Shaw | grad student | 2004 | University of Utah | |
| (The function of Mdm20p in yeast mitochondrial inheritance: Regulation of tropomyosin-actin interactions.) | ||||
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Publications
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| McClellan D, Casey MJ, Bareyan D, et al. (2019) Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation require Lysine Specific Demethylase (LSD)1-dependent recruitment of the BHC complex. Molecular and Cellular Biology |
| Velinder M, Singer J, Bareyan D, et al. (2017) GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. The Biochemical Journal. 474: 2951 |
| Andrade D, Velinder M, Singer J, et al. (2016) SUMOYLATION REGULATES GROWTH FACTOR INDEPENDENCE (GFI)-1 IN TRANSCRIPTIONAL CONTROL AND HEMATOPOIESIS. Molecular and Cellular Biology |
| Velinder ME, Singer J, Meznarich J, et al. (2015) GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis Blood. 126: 46-46 |
| Singer J, Andrade D, Bareyan D, et al. (2014) Abstract B19: Lysine specific demethylase-1 inhibition as a therapeutic strategy that leverages the requirement for growth factor independence-1 in Notch-driven T-ALL Cancer Research. 74 |
| Singer J, Andrade D, Bareyan D, et al. (2013) Notch Alters Sumoylation To Govern GFI1 Protein Stability and Support Its Transcriptional Repression Function Blood. 122: 3793-3793 |
| Andrade D, Singer J, Bareyan D, et al. (2013) Abstract LB-357: Notch and PIAS3 differentially regulate sumoylation of GFI1 to modulate transcriptional repression. Cancer Research. 73 |
| Andrade DL, Bareyan D, Singer J, et al. (2012) Abstract 3089: Regulation of GFI proteins by Notch intracellular domains Cancer Research. 72: 3089-3089 |
| Singer JM, Shaw JM. (2003) Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proceedings of the National Academy of Sciences of the United States of America. 100: 7644-9 |
| Singer JM, Hermann GJ, Shaw JM. (2000) Suppressors of mdm20 in yeast identify new alleles of ACT1 and TPM1 predicted to enhance actin-tropomyosin interactions. Genetics. 156: 523-34 |