Yvette Y. Yien, Ph.D.

Affiliations: 
2011 Developmental and Stem Cell Biology (DSCB) Mount Sinai School of Medicine, New York, NY 
Area:
Biochemistry
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"Yvette Yien"

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James J. Bieker grad student 2011 Mount Sinai
 (Regulation of the Erythroid Kruppel-Like Factor (EKLF): Beyond the basal transcription machinery.)
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Publications

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Yien YY, Perfetto M. (2022) Regulation of Heme Synthesis by Mitochondrial Homeostasis Proteins. Frontiers in Cell and Developmental Biology. 10: 895521
Rondelli CM, Perfetto M, Danoff A, et al. (2021) The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover. The Journal of Biological Chemistry. 100972
Perfetto M, Xu X, Lu C, et al. (2020) The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development (Cambridge, England)
Rondelli C, Danoff A, Bergonia H, et al. (2019) Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase Blood. 134: 427-427
Seguin A, Takahashi-Makise N, Yien YY, et al. (2017) Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes. The Journal of Biological Chemistry
Kardon JR, Yien YY, Huston NC, et al. (2015) Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis. Cell. 161: 858-67
Chung J, Bauer DE, Ghamari A, et al. (2015) The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Science Signaling. 8: ra34
Yien YY, Gnanapragasam MN, Gupta R, et al. (2015) Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues. Experimental Hematology. 43: 65-70
Yien YY, Bieker JJ. (2013) EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination. Molecular and Cellular Biology. 33: 4-13
Paw BH, Yien YY, Robledo RF, et al. (2013) Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism Blood. 122: 427-427
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