Kenrick M. Semple, Ph.D.

Affiliations: 
2011 Medical Sciences University of South Florida, Tampa, FL, United States 
Area:
Immunology
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"Kenrick Semple"

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Patricia A. Kruk grad student 2011 University of South Florida
 (Generation and Application of Antigen-Specific Induced Regulatory T cells in Allogeneic Bone Marrow Transplantation.)
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Publications

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Semple KM, Gonzaléz CM, Zarr M, et al. (2019) Evaluation of the ability of immune humanized mice to demonstrate CD20-specific cytotoxicity induced by ofatumumab. Clinical and Translational Science
Li J, Heinrichs J, Haarberg K, et al. (2015) HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease. Journal of Immunology (Baltimore, Md. : 1950). 195: 717-25
Chakraborty M, Fullerton AM, Semple K, et al. (2015) Drug-induced allergic hepatitis develops in mice when myeloid-derived suppressor cells are depleted prior to halothane treatment. Hepatology (Baltimore, Md.). 62: 546-57
Li J, Heinrichs J, Leconte J, et al. (2013) Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 200-7
Li J, Semple K, Heinrichs J, et al. (2012) High Efficacy of Alloantigen-Specific Induced Regulatory T Cells in the Prevention of Acute Graft-Versus-Host Disease in Mice Blood. 120: 4112-4112
Li J, Leconte J, Semple K, et al. (2012) PI3K-Independent Signaling Pathways Contribute to ICOS-Mediated T-Cell Costimulation in Acute Graft-Versus-Host Disease in Mice. Blood. 120: 3003-3003
Wang D, Yu Y, Semple KM, et al. (2012) Dynamic Changes and Impact of Myeloid Derived Suppressor Cells in Allogeneic Bone Marrow Transplantation in Mice. Blood. 120: 2999-2999
Yu Y, Wang D, Liu C, et al. (2011) Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice. Blood. 118: 5011-20
Li J, Semple K, Suh WK, et al. (2011) Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 17: 962-9
Semple K, Nguyen A, Yu Y, et al. (2011) Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling. Blood. 117: 3096-103
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