Gheorghe Proteasa, Ph.D.
Affiliations: | 2005 | Wayne State University, Detroit, MI, United States |
Area:
Biochemistry, Pharmaceutical ChemistryGoogle:
"Gheorghe Proteasa"Parents
Sign in to add mentorLadislau C. Kovari | grad student | 2005 | Wayne State | |
(Structure-function study of the HIV protease multi drug resistant clinical isolates.) |
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Publications
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Yedidi RS, Proteasa G, Martin PD, et al. (2014) A multi-drug resistant HIV-1 protease is resistant to the dimerization inhibitory activity of TLF-PafF. Journal of Molecular Graphics & Modelling. 53: 105-11 |
Yedidi RS, Proteasa G, Martinez JL, et al. (2011) Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants. Acta Crystallographica. Section D, Biological Crystallography. 67: 524-32 |
Proteasa G, Tahboub YR, Galijasevic S, et al. (2007) Kinetic evidence supports the existence of two halide binding sites that have a distinct impact on the heme iron microenvironment in myeloperoxidase. Biochemistry. 46: 398-405 |
Martin P, Vickrey JF, Proteasa G, et al. (2005) "Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target. Structure (London, England : 1993). 13: 1887-95 |
Martin P, Vickrey JF, Proteasa G, et al. (2005) Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target Structure. 13: 1887-1895 |
Logsdon BC, Vickrey JF, Martin P, et al. (2004) Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity. Journal of Virology. 78: 3123-32 |
Vickrey JF, Logsdon BC, Proteasa G, et al. (2003) HIV-1 protease variants from 100-fold drug resistant clinical isolates: expression, purification, and crystallization. Protein Expression and Purification. 28: 165-72 |