Chuan Shen, Ph.D.

Affiliations: 
2006 Iowa State University, Ames, IA, United States 
Area:
Genetics, Molecular Biology
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"Chuan Shen"

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Jo Anne Powell-Coffman grad student 2006 Iowa State
 (Studies of hypoxia response and regulation of hypoxia -inducible factor HIF-1 in Caenorhabditis elegans.)
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Publications

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Shen C, Kaelin WG. (2013) The VHL/HIF axis in clear cell renal carcinoma. Seminars in Cancer Biology. 23: 18-25
Shen C, Beroukhim R, Schumacher SE, et al. (2011) Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene. Cancer Discovery. 1: 222-35
Zhang Y, Shao Z, Zhai Z, et al. (2009) The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans. Plos One. 4: e6348
Shen C, Shao Z, Powell-Coffman JA. (2006) The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1. Genetics. 174: 1205-14
Shen C, Nettleton D, Jiang M, et al. (2005) Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans. The Journal of Biological Chemistry. 280: 20580-8
Shen C, Powell-Coffman JA. (2003) Genetic analysis of hypoxia signaling and response in C elegans. Annals of the New York Academy of Sciences. 995: 191-9
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