Natalie Strynadka
Affiliations: | Biochemistry and Molecular Biology | University of British Columbia, Vancouver, Vancouver, BC, Canada |
Area:
structure-based design of novel, therapeutically useful antibiotics and inhibitors of antibiotic-resistance mechanismsWebsite:
http://www.biochem.ubc.ca/faculty/natalie-strynadka/Google:
"Natalie Strynadka"Bio:
http://www.hhmi.org/research/sirs/strynadka_bio.html
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Michael N.G. James | grad student | 1990 | University of Alberta (Chemistry Tree) | |
| (Probing molecular interactions at various levels of structural definition) | ||||
Children
Sign in to add trainee| Steven R Ness | research assistant | 1997-2000 | Univesity of British Columia (UBC) (Chemistry Tree) |
| Nathanael A Caveney | grad student | (Chemistry Tree) | |
| Calvin Yip | grad student | UBC | |
| Trevor F. Moraes | post-doc | UBC |
BETA: Related publications
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Publications
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| Worrall LJ, Majewski DD, Strynadka NCJ. (2023) Structural Insights into Type III Secretion Systems of the Bacterial Flagellum and Injectisome. Annual Review of Microbiology. 77: 669-698 |
| Lee J, Kenward C, Worrall LJ, et al. (2022) X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nature Communications. 13: 5196 |
| Caveney NA, Workman SD, Yan R, et al. (2021) CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution. Nature Communications. 12: 2775 |
| Li FKK, Gale RT, Petrotchenko EV, et al. (2021) Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology. 107733 |
| Lyons BJE, Atkinson CE, Deng W, et al. (2021) Cryo-EM structure of the EspA filament from enteropathogenic Escherichia coli: revealing the mechanism of effector translocation in the T3SS. Structure (London, England : 1993) |
| Lee J, Worrall LJ, Vuckovic M, et al. (2020) Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nature Communications. 11: 5877 |
| Pazos M, Peters K, Boes A, et al. (2020) SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. Mbio. 11 |
| Majewski DD, Lyons BJE, Atkinson CE, et al. (2020) Cryo-EM analysis of the SctV cytosolic domain from the enteropathogenic E. coli T3SS injectisome. Journal of Structural Biology. 212: 107660 |
| Majewski DD, Okon M, Heinkel F, et al. (2020) Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure (London, England : 1993) |
| Alexander JAN, Radaeva M, King DT, et al. (2020) -Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant . The Journal of Biological Chemistry |