Bruce Alan Beutler
Affiliations: | University of Texas Southwestern Medical Center, Dallas, TX, United States |
Area:
innate immunityWebsite:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2011/beutler-bio.htmlGoogle:
"Bruce Beutler"Bio:
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity
and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity
.
http://www4.utsouthwestern.edu/beutlerlab/beutlerlab.html
http://www.aai.org/about/History/Notable_Members/Nobel/Beutler_Bruce.html
Cross-listing: ImmunoTree
Parents
Sign in to add mentorErnest Beutler | research assistant | City of Hope National Medical Center (Chemistry Tree) | |
Abraham I. Braude | research assistant | UCSD | |
Susumu Ohno | research assistant | City of Hope Medical Center | |
Anthony Cerami | post-doc | Rockefeller | |
Patricia Spear | research scientist | Chicago |
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Publications
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Jakkamsetti V, Ma Q, Angulo G, et al. (2023) Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion. Biorxiv : the Preprint Server For Biology |
Song R, McAlpine W, Fond AM, et al. (2023) Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation. Nature Communications. 14: 3652 |
Yuksel S, Aredo B, Zegeye Y, et al. (2023) Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis. Communications Biology. 6: 533 |
Khoenkhoen S, Ádori M, Solís-Sayago D, et al. (2022) IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens. Frontiers in Immunology. 13: 1000755 |
Zhang Z, Jiang Y, Su L, et al. (2022) Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis. Cell Metabolism |
Zhang Z, Xun Y, Rong S, et al. (2022) Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity. Nature Communications. 13: 4136 |
Yang MH, Russell JL, Mifune Y, et al. (2022) Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response. Journal of Medicinal Chemistry |
Chatenoud L, Marquet C, Valette F, et al. (2022) Modulation of autoimmune diabetes by ENU-induced mutations in non-obese diabetic mice. Disease Models & Mechanisms |
Zhong X, Choi JH, Hildebrand S, et al. (2022) RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200128119 |
Rimann I, Gonzalez-Quintial R, Baccala R, et al. (2022) The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200544119 |