Leonard F. Bjeldanes
Affiliations: | Nutritional Sciences & Toxicology | University of California, Berkeley, Berkeley, CA, United States |
Area:
Food toxicology; chemical carcinogenesisWebsite:
https://vcresearch.berkeley.edu/faculty/leonard-f-bjeldanesGoogle:
"Leonard Frank Bjeldanes"Bio:
Parents
Sign in to add mentor| Theodore A. Geissman | grad student | 1970 | UCLA (Chemistry Tree) | |
| (Constituents of heliantheae species.) | ||||
Children
Sign in to add trainee| Christopher Alan Bradfield | grad student | 1986 | UC Berkeley (Neurotree) |
| Chibo Hong | grad student | 2001 | UC Berkeley |
| Hoyee Leong | grad student | 2002 | UC Berkeley |
| Xiaofei Chang | grad student | 2005 | UC Berkeley |
| Yixuan Gong | grad student | 2005 | UC Berkeley |
| Holly L. Nicastro | grad student | 2010 | UC Berkeley |
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Publications
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| Chen H, Sohn J, Zhang L, et al. (2014) Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. European Journal of Pharmacology. 724: 168-74 |
| Nicastro HL, Firestone GL, Bjeldanes LF. (2013) 3,3'-diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells. The Journal of Nutritional Biochemistry. 24: 1882-8 |
| Johnson TA, Sohn J, Ward AE, et al. (2013) (+)-Altholactone exhibits broad spectrum immune modulating activity by inhibiting the activation of pro-inflammatory cytokines in RAW 264.7 cell lines. Bioorganic & Medicinal Chemistry. 21: 4358-64 |
| Johnson TA, Sohn J, Vaske YM, et al. (2012) Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. Bioorganic & Medicinal Chemistry. 20: 4348-55 |
| Feduccia AA, Wang Y, Simms JA, et al. (2012) Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacology, Biochemistry, and Behavior. 102: 241-8 |
| Aronchik I, Chen T, Durkin KA, et al. (2012) Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling. Molecular Carcinogenesis. 51: 881-94 |
| Marconett CN, Sundar SN, Tseng M, et al. (2011) Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells. Carcinogenesis. 32: 1315-23 |
| Nguyen HH, Lavrenov SN, Sundar SN, et al. (2010) 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells. Chemico-Biological Interactions. 186: 255-66 |
| Aronchik I, Bjeldanes LF, Firestone GL. (2010) Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells. Cancer Research. 70: 4961-71 |
| Vivar OI, Saunier EF, Leitman DC, et al. (2010) Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane. Endocrinology. 151: 1662-7 |