Michael Leffak

Affiliations: 
Wright State University, Fairborn, OH, United States 
Area:
Molecular Biology, Animal Physiology Biology, Cell Biology
Website:
https://people.wright.edu/michael.leffak
Google:
"Ira Michael Leffak" OR "Michael Leffak"
Bio:

https://www.proquest.com/openview/b5a1bd9c281644b181bb7f7105f508a7/1

Parents

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Hsueh Jei Li grad student 1976 CUNY (Chemistry Tree)
 (Physical Studies of Histone-DNA Interactions)
Harold Weintraub post-doc Princeton (Neurotree)
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Publications

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Gadgil RY, Rider SD, Shrestha R, et al. (2024) Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs. Nar Cancer. 6: zcae027
Gadgil RY, Rider SD, Shrestha R, et al. (2024) Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs. Biorxiv : the Preprint Server For Biology
Rider SD, Damewood FJ, Gadgil RY, et al. (2023) Suppressors of Break-Induced Replication in Human Cells. Genes. 14
Rider SD, Gadgil RY, Hitch DC, et al. (2022) Stable G-quadruplex DNA structures promote replication-dependent genome instability. The Journal of Biological Chemistry. 101947
Gadgil RY, Romer EJ, Goodman CC, et al. (2020) Replication stress at microsatellites causes DNA double strand breaks and break induced replication. The Journal of Biological Chemistry
Gadgil RY, Rider SD, Lewis T, et al. (2020) Analysis of Trinucleotide Repeat Stability by Integration at a Chromosomal Ectopic Site. Methods in Molecular Biology (Clifton, N.J.). 2056: 121-136
Lewis TW, Barthelemy JR, Virts EL, et al. (2019) Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination. Nucleic Acids Research
Poudel S, Yao J, Kemp MG, et al. (2018) Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells. The Journal of Biological Chemistry
Leffak M. (2017) Break-induced replication links microsatellite expansion to complex genome rearrangements. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
Leffak M, Gadgil R, Barthelemy J, et al. (2016) Replication stalling and DNA microsatellite instability. Biophysical Chemistry
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