Hsin-Hsiung Tai
Affiliations: | University of Kentucky, Lexington, KY |
Area:
Molecular Biology, PharmacologyGoogle:
"Hsin-Hsiung Tai"
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Publications
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Li X, Tai HH. (2014) Thromboxane A2 receptor-mediated release of matrix metalloproteinase-1 (MMP-1) induces expression of monocyte chemoattractant protein-1 (MCP-1) by activation of protease-activated receptor 2 (PAR2) in A549 human lung adenocarcinoma cells. Molecular Carcinogenesis. 53: 659-66 |
Li X, Tai HH. (2013) Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells. Plos One. 8: e54073 |
Li X, Tai HH. (2012) Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells. Current Cancer Drug Targets. 12: 703-15 |
Tai HH. (2011) Prostaglandin catabolic enzymes as tumor suppressors. Cancer Metastasis Reviews. 30: 409-17 |
Tai HH, Chi X, Tong M. (2011) Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). Prostaglandins & Other Lipid Mediators. 96: 37-40 |
Wu Y, Karna S, Choi CH, et al. (2011) Synthesis and biological evaluation of novel thiazolidinedione analogues as 15-hydroxyprostaglandin dehydrogenase inhibitors. Journal of Medicinal Chemistry. 54: 5260-4 |
Hamza A, Tong M, AbdulHameed MD, et al. (2010) Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis. The Journal of Physical Chemistry. B. 114: 5605-16 |
Wu Y, Tai HH, Cho H. (2010) Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors. Bioorganic & Medicinal Chemistry. 18: 1428-33 |
Wei J, Yan W, Li X, et al. (2010) Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells. Lung Cancer (Amsterdam, Netherlands). 69: 26-32 |
Zhao Y, Weng CC, Tong M, et al. (2010) Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo. Lung Cancer (Amsterdam, Netherlands). 68: 161-9 |