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Rebecca Taub

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Genetics
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"Rebecca Taub"
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Julia I. Leu grad student 2001 Penn
Charles A. Peters grad student 2003 Penn

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Publications

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Harrison SA, Bedossa P, Guy CD, et al. (2024) A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. The New England Journal of Medicine. 390: 497-509
Harrison SA, Ratziu V, Anstee QM, et al. (2023) Design of the phase 3 MAESTRO clinical program to evaluate resmetirom for the treatment of nonalcoholic steatohepatitis. Alimentary Pharmacology & Therapeutics
Harrison SA, Bashir MR, Guy CD, et al. (2019) Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. Lancet (London, England)
Harrison S, Guy C, Taub R, et al. (2019) SAT-347-MRI-PDFF response in MGL-3196 and placebo treated patients predicts reduction in ballooning and inflammation components of NAS and NASH resolution in a 36-week serial liver biopsy study Journal of Hepatology. 70
Harrison S, Moussa S, Bashir M, et al. (2018) MGL-3196, a selective thyroid hormone receptor-beta agonist significantly decreases hepatic fat in NASH patients at 12 weeks, the primary endpoint in a 36 week serial liver biopsy study Journal of Hepatology. 68
Jiao Y, Ye DZ, Li Z, et al. (2015) Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G85-91
Zelent D, Golson ML, Koeberlein B, et al. (2006) A glucose sensor role for glucokinase in anterior pituitary cells. Diabetes. 55: 1923-9
Sagen JV, Odili S, Bjørkhaug L, et al. (2006) From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation. Diabetes. 55: 1713-22
DeAngelis RA, Markiewski MM, Taub R, et al. (2005) A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha. Hepatology (Baltimore, Md.). 42: 1148-57
Taub R. (2005) Adenovirus-mediated overexpression of activin beta(C) subunit accelerates liver regeneration in partially hepatectomized rats. Journal of Hepatology. 43: 751-3
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