Frederic Kaye

Affiliations: 
The George Washington University, Washington, DC, United States 
Area:
Genetics, Oncology, Molecular Biology
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"Frederic Kaye"
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Publications

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Guijarro MV, Nawab A, Dib P, et al. (2023) TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background. Oncogene
Khan S, Kellish P, Connis N, et al. (2023) Co-targeting BCL-X and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice. Cell Death Discovery. 9: 1
Khan S, Wiegand J, Zhang P, et al. (2022) BCL-X PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS-mutated cancers. Journal of Hematology & Oncology. 15: 23
Creelan BC, Wang C, Teer JK, et al. (2021) Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial. Nature Medicine
Zhou X, Li JW, Chen Z, et al. (2021) Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation. Elife. 10
Chen Z, Ni W, Li JL, et al. (2021) The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma. Jci Insight. 6
George TJ, DeRemer DL, Parekh HD, et al. (2020) Phase II trial of the PARP inhibitor, niraparib, in BAP1 and other DNA damage response (DDR) pathway deficient neoplasms including cholangiocarcinoma. Journal of Clinical Oncology. 38: TPS591-TPS591
ali a, DeRemer DL, Lee J, et al. (2020) Phase II trial of the PARP inhibitor, niraparib, in BAP1 and other DNA damage response (DDR) pathway deficient neoplasms (NCT03207347). Journal of Clinical Oncology. 38: e22061-e22061
Stewart BD, Kaye F, Machuca T, et al. (2019) SMARCA4-Deficient Thoracic Sarcoma: A Case Report and Review of Literature. International Journal of Surgical Pathology. 1066896919865944
Tasoulas J, Rodon L, Kaye FJ, et al. (2019) Adaptive Transcriptional Responses by CRTC Coactivators in Cancer. Trends in Cancer. 5: 111-127
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