Prashant K. Nighot, Ph.D.
Affiliations: | 2008 | North Carolina State University, Raleigh, NC |
Area:
Physiology Biology, Cell BiologyGoogle:
"Prashant Nighot"Parents
Sign in to add mentor| Anthony Blikslager | grad student | 2008 | NCSU | |
| (Role of ClC-2 and NHE transport proteins in intestinal mucosal barrier.) | ||||
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Publications
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| Arumugam P, Saha K, Nighot P. (2024) Intestinal Epithelial Tight Junction Barrier Regulation by Novel Pathways. Inflammatory Bowel Diseases |
| Saha K, Subramenium Ganapathy A, Wang A, et al. (2023) Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation. Mucosal Immunology |
| Ganapathy AS, Saha K, Wang A, et al. (2023) Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways. Cell Reports. 42: 112705 |
| Nighot M, Liao PL, Morris N, et al. (2022) Long term use of Proton Pump Inhibitor disrupts intestinal tight junction barrier and exaggerates experimental colitis. Journal of Crohn's & Colitis |
| Saha K, Ganapathy AS, Wang A, et al. (2022) Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux. Journal of Crohn's & Colitis |
| Ganapathy AS, Saha K, Suchanec E, et al. (2021) AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability. Autophagy. 1-18 |
| Al-Sadi R, Dharmaprakash V, Nighot P, et al. (2021) Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner. International Journal of Molecular Sciences. 22 |
| Nighot M, Ganapathy AS, Saha K, et al. (2021) Matrix Metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis. Journal of Crohn's & Colitis |
| Al-Sadi R, Nighot P, Nighot M, et al. (2021) Lactobacillus acidophilus induces a strain-specific and toll-like receptor-2 dependent enhancement of intestinal epithelial tight junction barrier and protection against intestinal inflammation. The American Journal of Pathology |
| Nighot P, Ma T. (2020) Endocytosis of Intestinal Tight Junction Proteins: In Time and Space. Inflammatory Bowel Diseases |