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Jessica K. Wickenheisser, Ph.D.

Affiliations: 
2002 Pennsylvania State University, State College, PA, United States 
Area:
Molecular Biology
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"Jessica Wickenheisser"
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Jan M. McAllister grad student 2002 Penn State
 (Transcriptional regulation of the 17alpha-hydroxylase gene in normal and polycystic ovary syndrome ovarian theca cells.)

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Wickenheisser JK, Biegler JM, Nelson-Degrave VL, et al. (2012) Cholesterol side-chain cleavage gene expression in theca cells: augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome. Plos One. 7: e48963
Chen C, Wickenheisser J, Ewens KG, et al. (2009) PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women. Molecular Human Reproduction. 15: 459-69
Chen C, Wickenheisser J, Ewens KG, et al. (2009) PDE8A Genetic Variation Is Not Associated with Polycystic Ovary Syndrome. Biology of Reproduction. 81: 364-364
Wickenheisser JK, Nelson-DeGrave VL, McAllister JM. (2006) Human ovarian theca cells in culture. Trends in Endocrinology and Metabolism: Tem. 17: 65-71
Ho CK, Wood JR, Stewart DR, et al. (2005) Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells. The Journal of Clinical Endocrinology and Metabolism. 90: 6596-602
Wickenheisser JK, Nelson-DeGrave VL, Hendricks KL, et al. (2005) Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism. 90: 4858-65
Wickenheisser JK, Nelson-Degrave VL, McAllister JM. (2005) Dysregulation of cytochrome P450 17alpha-hydroxylase messenger ribonucleic acid stability in theca cells isolated from women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism. 90: 1720-7
Nelson-Degrave VL, Wickenheisser JK, Hendricks KL, et al. (2005) Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome. Molecular Endocrinology (Baltimore, Md.). 19: 379-90
Wickenheisser JK, Nelson-DeGrave VL, Quinn PG, et al. (2004) Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1. Molecular Endocrinology (Baltimore, Md.). 18: 588-605
Nelson-DeGrave VL, Wickenheisser JK, Cockrell JE, et al. (2004) Valproate potentiates androgen biosynthesis in human ovarian theca cells. Endocrinology. 145: 799-808
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