Stuart Milstein, Ph.D.

Affiliations: 
2001 Stony Brook University, Stony Brook, NY, United States 
Area:
Genetics, Animal Physiology Biology
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"Stuart Milstein"

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Michael Hengartner grad student 2001 SUNY Stony Brook
 (Genetic analysis of programmed cell death in the Caenorhabditis elegans germ line.)
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Publications

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Mancio-Silva L, Fleming HE, Miller AB, et al. (2019) Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers. Cell Metabolism. 29: 727-735.e3
Foster DJ, Brown CR, Shaikh S, et al. (2018) Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates. Molecular Therapy : the Journal of the American Society of Gene Therapy
Singh KD, Zheng X, Milstein S, et al. (2017) Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans. Plos One. 12: e0182270
Milstein S, Qian K, Zhang L, et al. (2017) Methods to Identify and Characterize siRNAs Targeting Serpin A1 In Vitro and In Vivo Using RNA Interference. Methods in Molecular Biology (Clifton, N.J.). 1639: 115-126
Butler JS, Chan A, Costelha S, et al. (2016) Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-10
Chan A, Liebow A, Yasuda M, et al. (2015) Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification. Molecular Therapy. Nucleic Acids. 4: e263
Rajeev KG, Nair JK, Jayaraman M, et al. (2015) Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo. Chembiochem : a European Journal of Chemical Biology. 16: 903-8
Matsuda S, Keiser K, Nair JK, et al. (2015) siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytes. Acs Chemical Biology. 10: 1181-7
Rajeev KG, Nair JK, Jayaraman M, et al. (2015) Cover Picture: Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo (ChemBioChem 6/2015) Chembiochem. 16: 873-873
Nair JK, Willoughby JL, Chan A, et al. (2014) Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing. Journal of the American Chemical Society. 136: 16958-61
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