Jodi L. Karnell, Ph.D.

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Jodi Karnell"

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Laurence A. Turka grad student 2008 Penn
 (Regulation of CD4+ T cell responses by PTEN.)
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Publications

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Abdeladhim M, Karnell JL, Rieder SA. (2022) In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways. Frontiers in Immunology. 13: 1033705
Karnell JL, Wu Y, Mittereder N, et al. (2021) Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus. Science Translational Medicine. 13
Rieder SA, Wang J, White N, et al. (2020) B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling. Cellular & Molecular Immunology
Gonzalez Cardona J, Smith MD, Wang J, et al. (2019) Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis. Plos One. 14: e0221747
Kirby L, Jin J, Cardona JG, et al. (2019) Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination. Nature Communications. 10: 3887
Karnell JL, Albulescu M, Drabic S, et al. (2019) A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity. Science Translational Medicine. 11
Varkey R, Du Q, Karnell JL, et al. (2019) Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy. Plos One. 14: e0211236
Wang S, Maul RW, Kumar V, et al. (2019) 45 CD11c-hi T-bet+ B cells contribute to the pathogenesis of SLE through generation of autoreactive plasma cells Lupus Science & Medicine. 6
Karnell JL, Rieder SA, Ettinger R, et al. (2018) Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond. Advanced Drug Delivery Reviews
Wang S, Wang J, Kumar V, et al. (2018) IL-21 drives expansion and plasma cell differentiation of autoreactive CD11cT-bet B cells in SLE. Nature Communications. 9: 1758
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