Carolyn C. Spaulding, Ph.D.

Affiliations: 
2000 University of California, Los Angeles, Los Angeles, CA 
Area:
Immunology, Cell Biology, Gerontology
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"Carolyn Spaulding"

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Rita B. Effros grad student 2000 UCLA
 (Age related dysregulation of immune function.)
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Publications

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Effros RB, Dagarag M, Spaulding C, et al. (2005) The role of CD8+ T-cell replicative senescence in human aging. Immunological Reviews. 205: 147-57
Spaulding C, Guo W, Effros RB. (1999) Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation. Experimental Gerontology. 34: 633-44
Spaulding CC, Walford RL, Effros RB. (1997) Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-alpha and IL-6 in C3B10RF1 mice. Mechanisms of Ageing and Development. 93: 87-94
Spaulding CC, Walford RL, Effros RB. (1997) The accumulation of non-replicative, non-functional, senescent T cells with age is avoided in calorically restricted mice by an enhancement of T cell apoptosis. Mechanisms of Ageing and Development. 93: 25-33
Effros RB, Boucher N, Porter V, et al. (1994) Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence Experimental Gerontology. 29: 601-609
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