Layton H. Smith, Ph.D.
Affiliations: | 2002 | Vanderbilt University, Nashville, TN |
Area:
PharmacologyGoogle:
"Layton Smith"Parents
Sign in to add mentorDouglas E. Vaughan | grad student | 2002 | Vanderbilt | |
(Cholesterol-regulated gene expression in vascular endothelial cells.) |
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Publications
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Rai R, Ghosh AK, Eren M, et al. (2017) Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan. Cell Reports. 21: 1471-1480 |
Boe AE, Eren M, Murphy SB, et al. (2013) Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence. Circulation. 128: 2318-24 |
Siddiquee K, Hampton J, Khan S, et al. (2011) Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production. Journal of Hypertension. 29: 724-31 |
Smith LH, Dixon JD, Stringham JR, et al. (2006) Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis. Blood. 107: 132-4 |
De Taeye B, Smith LH, Vaughan DE. (2005) Plasminogen activator inhibitor-1: a common denominator in obesity, diabetes and cardiovascular disease. Current Opinion in Pharmacology. 5: 149-54 |
Smith LH, Petrie MS, Morrow JD, et al. (2005) The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells. Journal of Lipid Research. 46: 862-71 |
Shaklee JF, Talbot TR, Muldowney JA, et al. (2005) Smallpox vaccination does not elevate systemic levels of prothrombotic proteins associated with ischemic cardiac events. The Journal of Infectious Diseases. 191: 724-30 |
Smith LH, Coats SR, Qin H, et al. (2004) Differential and opposing regulation of PAI-1 promoter activity by estrogen receptor alpha and estrogen receptor beta in endothelial cells. Circulation Research. 95: 269-75 |
Schoenhard JA, Smith LH, Painter CA, et al. (2003) Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2. Journal of Molecular and Cellular Cardiology. 35: 473-81 |
Smith LH, Boutaud O, Breyer M, et al. (2002) Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 983-8 |