Brian A. Roelofs, Ph.D.
Affiliations: | 2012 | Biochemistry and Molecular Biology | Johns Hopkins University, Baltimore, MD |
Area:
BiochemistryGoogle:
"Brian Roelofs"Parents
Sign in to add mentor| J. Marie Hardwick | grad student | Johns Hopkins Bloomberg School of Public Health (Neurotree) | ||
| Marie Hardwick | grad student | 2012 | Johns Hopkins | |
| (Post-translational modifications of BCL-xL orchestrate non-canonical functions.) | ||||
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Publications
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| Aubrecht TG, Faden AI, Sabirzhanov B, et al. (2018) Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury. Cell Death & Disease. 9: 1121 |
| Bordt EA, Clerc P, Roelofs BA, et al. (2017) The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species. Developmental Cell. 40: 583-594.e6 |
| Xu S, Cherok E, Das S, et al. (2015) Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein. Molecular Biology of the Cell |
| Roelofs BA, Ge SX, Studlack PE, et al. (2015) Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV. Free Radical Biology & Medicine. 86: 250-8 |
| Polster BM, Nicholls DG, Ge SX, et al. (2014) Use of potentiometric fluorophores in the measurement of mitochondrial reactive oxygen species. Methods in Enzymology. 547: 225-50 |
| Karbowski M, Cleland MM, Roelofs BA. (2014) Photoactivatable green fluorescent protein-based visualization and quantification of mitochondrial fusion and mitochondrial network complexity in living cells. Methods in Enzymology. 547: 57-73 |
| McNally MA, Soane L, Roelofs BA, et al. (2013) The N-terminal helix of Bcl-xL targets mitochondria. Mitochondrion. 13: 119-24 |
| Ofengeim D, Chen YB, Miyawaki T, et al. (2012) N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nature Neuroscience. 15: 574-80 |
| Roelofs BA, Hardwick JM. (2011) Flying to a halt: Drosophila Aven arrests the cell cycle. Cell Cycle (Georgetown, Tex.). 10: 1350-51 |