Daniel R. Beisner, Ph.D.
Affiliations: | 2005 | University of California, San Diego, La Jolla, CA |
Area:
Immunology, Cell BiologyGoogle:
"Daniel Beisner"Parents
Sign in to add mentor| Stephen M Hedrick | grad student | 2005 | UCSD | |
| (The role of death receptor signaling molecules in T and B lymphocyte proliferation and survival.) | ||||
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Publications
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| Velcicky J, Mathison CJN, Nikulin V, et al. (2019) Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. Acs Medicinal Chemistry Letters. 10: 887-892 |
| Velcicky J, Bodendorf U, Rigollier P, et al. (2018) Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo. Journal of Medicinal Chemistry |
| Miller AT, Dahlberg C, Sandberg ML, et al. (2015) Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease. Plos One. 10: e0131071 |
| Beisner DR, Langerak P, Parker AE, et al. (2013) The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain. The Journal of Experimental Medicine. 210: 23-30 |
| Kerdiles YM, Stone EL, Beisner DR, et al. (2010) Foxo transcription factors control regulatory T cell development and function. Immunity. 33: 890-904 |
| Dejean AS, Beisner DR, Ch'en IL, et al. (2009) Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nature Immunology. 10: 504-13 |
| Miller AT, Beisner DR, Liu D, et al. (2009) Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 182: 4696-704 |
| Kerdiles YM, Beisner DR, Tinoco R, et al. (2009) Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nature Immunology. 10: 176-84 |
| Ch'en IL, Beisner DR, Degterev A, et al. (2008) Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences of the United States of America. 105: 17463-8 |
| Ch'en IL, Beisner DR, Degterev A, et al. (2008) Caspase‐8 regulates a form of death that is distinct from apoptosis in T cells The Faseb Journal. 22: 369-369 |