Nicole H. Purcell, Ph.D.
Affiliations: | 2001 | University of Alabama, Birmingham, Birmingham, AL, United States |
Area:
Cell Biology, Molecular BiologyGoogle:
"Nicole Purcell"Parents
Sign in to add mentor| Anning Lin | grad student | 2001 | UAB | |
| (The role of the transcription factor nuclear factor-kappaB in cellular stress responses.) | ||||
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Publications
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| Yeh ST, Zambrano CM, Koch WJ, et al. (2018) PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) Regulates G-protein coupled Receptor Kinase 5 (GRK5) induced Cardiac Hypertrophy . The Journal of Biological Chemistry |
| Dusaban SS, Purcell NH, Rockenstein E, et al. (2013) Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 3609-14 |
| Maillet M, Purcell NH, Sargent MA, et al. (2008) DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility. The Journal of Biological Chemistry. 283: 31246-55 |
| Purcell NH, Wilkins BJ, York A, et al. (2007) Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 14074-9 |
| Lips DJ, Bueno OF, Wilkins BJ, et al. (2004) MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation. 109: 1938-41 |
| Purcell NH, Darwis D, Bueno OF, et al. (2004) Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. Molecular and Cellular Biology. 24: 1081-95 |
| Purcell NH, Molkentin JD. (2003) Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy? Circulation. 108: 638-40 |
| Gupta S, Purcell NH, Lin A, et al. (2002) Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. The Journal of Cell Biology. 159: 1019-28 |
| Tang G, Minemoto Y, Dibling B, et al. (2001) Inhibition of JNK activation through NF-kappaB target genes. Nature. 414: 313-7 |
| Purcell NH, Tang G, Yu C, et al. (2001) Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 6668-73 |