John E. Mata, Ph.D.

Affiliations: 
2000 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacology, Molecular Biology, Cell Biology
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"John Mata"

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Patrick L. Iversen grad student 2000 University of Nebraska Medical Center
 (Applications and limitations of oligonucleotide based therapeutics.)
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Publications

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Knapp DC, Mata JE, Reddy MT, et al. (2003) Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model. Anti-Cancer Drugs. 14: 39-47
Ricker JL, Mata JE, Iversen PL, et al. (2002) c-myc antisense oligonucleotide treatment ameliorates murine ARPKD. Kidney International. 61: S125-31
Mata JE, Bishop MR, Tarantolo SR, et al. (2000) Evidence of enhanced iron excretion during systemic phosphorothioate oligodeoxynucleotide treatment. Journal of Toxicology. Clinical Toxicology. 38: 383-7
Mata JE, Jackson JD, Joshi SS, et al. (2000) Pharmacokinetics and in vivo effects of a six-base phosphorothioate oligodeoxynucleotide with anticancer and hematopoietic activities in swine. Journal of Hematotherapy & Stem Cell Research. 9: 205-14
Iversen PL, Cornish KG, Iversen LJ, et al. (1999) Bolus intravenous injection of phosphorothioate oligonucleotides causes hypotension by acting as alpha(1)-adrenergic receptor antagonists. Toxicology and Applied Pharmacology. 160: 289-96
Page TJ, Mata JE, Bridge JA, et al. (1999) The cytotoxic effects of single-stranded telomere mimics on OMA-BL1 cells. Experimental Cell Research. 252: 41-9
Takeda A, Hisada H, Okada S, et al. (1997) Tumor cell growth is inhibited by suppressing metallothionein-I synthesis. Cancer Letters. 116: 145-9
Mata JE, Joshi SS, Palen B, et al. (1997) A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo. Toxicology and Applied Pharmacology. 144: 189-97
Desjardins J, Mata J, Brown T, et al. (1995) Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo. Journal of Drug Targeting. 2: 477-485
Wang M, Mata J, Price CE, et al. (1995) Prenatal and presymptomatic diagnosis of the Marfan syndrome using fluorescence PCR and an automated sequencer. Prenatal Diagnosis. 15: 499-507
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