Lauranell H. Burch, Ph.D.

Affiliations: 
2001 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Biology
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"Lauranell Burch"

Parents

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Richard C. Boucher grad student 2001 UNC Chapel Hill
 (Tissue -specific forms of CFTR.)
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Publications

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Burch LH. (2011) MUC5B promoter polymorphism and pulmonary fibrosis. The New England Journal of Medicine. 365: 178; author reply 17
Taylor-Cousar JL, Zariwala MA, Burch LH, et al. (2009) Histo-blood group gene polymorphisms as potential genetic modifiers of infection and cystic fibrosis lung disease severity. Plos One. 4: e4270
Burch LH, Picher M. (2006) E-NTPDases in human airways: Regulation and relevance for chronic lung diseases. Purinergic Signalling. 2: 399-408
Highsmith WE, Friedman KJ, Burch LH, et al. (2005) A CFTR mutation (D1152H) in a family with mild lung disease and normal sweat chlorides. Clinical Genetics. 68: 88-90
Voynow JA, Fischer BM, Malarkey DE, et al. (2004) Neutrophil elastase induces mucus cell metaplasia in mouse lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L1293-302
Picher M, Burch LH, Boucher RC. (2004) Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis. The Journal of Biological Chemistry. 279: 20234-41
Gray T, Coakley R, Hirsh A, et al. (2004) Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L320-30
Picher M, Burch LH, Hirsh AJ, et al. (2003) Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. The Journal of Biological Chemistry. 278: 13468-79
Highsmith WE, Burch LH, Zhou Z, et al. (1997) Identification of a splice site mutation (2789 +5 G > A) associated with small amounts of normal CFTR mRNA and mild cystic fibrosis. Human Mutation. 9: 332-8
Burch LH, Talbot CR, Knowles MR, et al. (1995) Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. The American Journal of Physiology. 269: C511-8
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