Hongfang Wang, Ph.D.

Affiliations: 
2006 University of Utah, Salt Lake City, UT 
Area:
Immunology
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"Hongfang Wang"

Parents

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Gerald J. Spangrude grad student 2002-2006 University of Utah
 (Characterization of thymocyte progenitors in adult bone marrow and effects of cytokines on T cell development.)
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Publications

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Severson E, Arnett KL, Wang H, et al. (2017) Genome-wide identification and characterization of Notch transcription complex-binding sequence-paired sites in leukemia cells. Science Signaling. 10
Wang H, Zang C, Liu XS, et al. (2015) The role of Notch receptors in transcriptional regulation. Journal of Cellular Physiology. 230: 982-8
Yashiro-Ohtani Y, Wang H, Zang C, et al. (2014) Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: E4946-53
Knoechel B, Roderick JE, Williamson KE, et al. (2014) An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nature Genetics. 46: 364-70
Wang H, Zang C, Taing L, et al. (2014) NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 705-10
Grayson AR, Walsh EM, Cameron MJ, et al. (2014) MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma Oncogene. 33: 1736-1742
Wang H, Yashiro-Ohtani Y, Zang C, et al. (2014) Alternative Super-Enhancer States Determine MYC Sensitivity to Notch and Brd4 Inhibitors in T Lymphoblastic Leukemia/Lymphoma Blood. 124: 863-863
Knoechel B, Roderick J, Williamson K, et al. (2014) Abstract 4782: Epigenetic resistance to Notch inhibition in T cell acute lymphoblastic leukemia Cancer Research. 74: 4782-4782
Kluk MJ, Ashworth T, Wang H, et al. (2013) Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. Plos One. 8: e67306
Manning J, Mitchell B, Appadurai DA, et al. (2013) Vitamin C promotes maturation of T-cells. Antioxidants & Redox Signaling. 19: 2054-67
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