Matthew H. Herynk, Ph.D.
Affiliations: | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Cell Biology, OncologyGoogle:
"Matthew Herynk"Parents
Sign in to add mentor| Gary Gallick | grad student | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
| (Activation of c -Met contributes to growth and metastasis of human colorectal carcinoma.) | ||||
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Publications
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| Patel SA, Herynk MH, Cascone T, et al. (2021) Estrogen promotes resistance to bevacizumab in murine models of non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer |
| Cascone T, Herynk MH, Xu L, et al. (2011) Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. The Journal of Clinical Investigation. 121: 1313-28 |
| Barone I, Cui Y, Herynk MH, et al. (2009) Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway. Cancer Research. 69: 4724-32 |
| Herynk MH, Zhang J, Parikh NU, et al. (2007) Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells. Journal of Experimental Therapeutics & Oncology. 6: 205-17 |
| Herynk MH, Beyer AR, Cui Y, et al. (2006) Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells. Molecular Cancer Therapeutics. 5: 3023-31 |
| Minard ME, Herynk MH, Collard JG, et al. (2005) The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. Oncogene. 24: 2568-73 |
| Kim SJ, Johnson M, Koterba K, et al. (2003) Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5161-70 |
| Herynk MH, Tsan R, Radinsky R, et al. (2003) Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin. Clinical & Experimental Metastasis. 20: 291-300 |
| Herynk MH, Stoeltzing O, Reinmuth N, et al. (2003) Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells. Cancer Research. 63: 2990-6 |