Martin Loignon, Ph.D.

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology, Cell Biology, Oncology
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"Martin Loignon"

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Elliot Drobetsky grad student 2002 Université de Montréal
 (Roles de la voie regulatrice p53/p21(waf1)/PRB dans la reponse aux dommages induits par les UV dans les cellules humaines.)
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Publications

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Rouget R, Auclair Y, Loignon M, et al. (2008) A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells. The Journal of Biological Chemistry. 283: 5533-41
Loignon M, Amrein L, Dunn M, et al. (2007) XRCC3 depletion induces spontaneous DNA breaks and p53-dependent cell death. Cell Cycle (Georgetown, Tex.). 6: 606-11
Xu ZY, Loignon M, Han FY, et al. (2005) Xrcc3 induces cisplatin resistance by stimulation of Rad51-related recombinational repair, S-phase checkpoint activation, and reduced apoptosis. The Journal of Pharmacology and Experimental Therapeutics. 314: 495-505
Loignon M, Drobetsky EA. (2002) The initiation of UV-induced G(1) arrest in human cells is independent of the p53/p21/pRb pathway but can be attenuated through expression of the HPV E7 oncoprotein. Carcinogenesis. 23: 35-45
Therrien JP, Loignon M, Drouin R, et al. (2001) Ablation of p21waf1cip1 expression enhances the capacity of p53-deficient human tumor cells to repair UVB-induced DNA damage. Cancer Research. 61: 3781-6
Loignon M, Fetni R, Gordon AJ, et al. (1997) A p53-independent pathway for induction of p21waf1cip1 and concomitant G1 arrest in UV-irradiated human skin fibroblasts. Cancer Research. 57: 3390-4
Drobetsky EA, Loignon M, Leger C, et al. (1997) O XI A.3 Wavelength dependence of UV mutagenesis in mammalian cells Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S78
Loignon M, Fetni R, Drobetsky E. (1997) P VII.1 Induction of p21cip1/waf1 and concomitant G1 arrest are p53-independent in UVC-irradiated human fibroblasts Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S48
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