Spiro Getsios, Ph.D.

Affiliations: 
2001 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Obstetrics and Gynecology, Cell Biology
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"Spiro Getsios"

Parents

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Colin D. MacCalman grad student 2001 UBC
 (Cadherin -mediated differentiation and fusion of human trophoblastic cells in vitro.)
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Publications

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Olalekan SA, Burdette JE, Getsios S, et al. (2017) Development of a Novel Human Recellularized Endometrium that responds to a 28 day Hormone Treatment. Biology of Reproduction
Brooks YS, Ostano P, Jo SH, et al. (2014) Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer. The Journal of Clinical Investigation. 124: 2260-76
Dai J, Brooks Y, Lefort K, et al. (2013) The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1. Plos One. 8: e70392
Simpson CL, Kojima SI, Cooper-Whitehair V, et al. (2010) Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: Implications for exfoliative toxin-mediated skin blistering American Journal of Pathology. 177: 2921-2937
Dusek RL, Godsel LM, Chen F, et al. (2007) Plakoglobin deficiency protects keratinocytes from apoptosis Journal of Investigative Dermatology. 127: 792-801
Yin T, Getsios S, Caldelari R, et al. (2005) Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. The Journal of Biological Chemistry. 280: 40355-63
Yin T, Getsios S, Caldelari R, et al. (2005) Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 102: 5420-5
Getsios S, Amargo EV, Dusek RL, et al. (2004) Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion Differentiation. 72: 419-433
Lorch JH, Klessner J, Park JK, et al. (2004) Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells. The Journal of Biological Chemistry. 279: 37191-200
Patel IS, Madan P, Getsios S, et al. (2003) Cadherin switching in ovarian cancer progression International Journal of Cancer. 106: 172-177
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