Bertrand Jean-Claude
Affiliations: | McGill University, Montreal, QC, Canada |
Area:
Oncology, Cell BiologyGoogle:
"Bertrand Jean-Claude"
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Publications
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| Facchin C, Fraga-Timiraos AB, Schmitt J, et al. (2023) Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model. Cells. 12 |
| Rao S, Thibault B, Peyrard L, et al. (2021) Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting. International Journal of Molecular Sciences. 22 |
| Golabi N, Larroque AL, Peyrard L, et al. (2020) Subcellular distribution and mechanism of action of AL906, a novel and potent EGFR inhibitor rationally designed to be green fluorescent. Investigational New Drugs |
| Schmitt J, Huang S, Goodfellow E, et al. (2020) Design and Synthesis of a Trifunctional Molecular System "Programmed" to Block Epidermal Growth Factor Receptor Tyrosine Kinase, Induce High Levels of DNA Damage, and Inhibit the DNA Repair Enzyme (Poly(ADP-ribose) Polymerase) in Prostate Cancer Cells. Journal of Medicinal Chemistry |
| Schmitt J, Goodfellow E, Huang S, et al. (2020) Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules. European Journal of Medicinal Chemistry. 192: 112185 |
| Gamero-Estevez E, Andonian S, Jean-Claude B, et al. (2019) Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells. International Journal of Molecular Sciences. 20 |
| Sharifi Z, Abdulkarim B, Meehan B, et al. (2019) Antitumor Activity of a Binary EGFR/DNA Targeting Strategy Overcomes Resistance of Glioblastoma Stem cells to Temozolomide. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Jusu S, Presley J, Jean-Claude B, et al. (2019) Abstract LB-024: Inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1): evidence for impaired vitamin D signaling in an MMTV-PYMT mouse model of breast cancer Cancer Research. 79 |
| Raveendrakumar R, Abdulkarim B, Bagchi M, et al. (2019) EXTH-50. THIOREDOXIN REDUCTASE1 AND MGMT SYNTHETIC LETHALITY ENHANCES CYTOTOXICITY OF PRIMA-1MET(APR-246) AND AURANOFIN IN GLIOBLASTOMA Neuro-Oncology. 21: vi93-vi93 |
| Rupp M, Mouhri ZS, Williams C, et al. (2018) Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O-methylguanine-DNA methyltransferase with a double arm hybrid molecule. Oncotarget. 9: 35041-35055 |