Jeffrey L. Wrana
Affiliations: | University of Toronto, Toronto, ON, Canada |
Area:
Cell Biology, Molecular BiologyGoogle:
"Jeffrey Wrana"Bio:
Jeffrey Wrana is based at the Samuel Lunenfeld Research
Institute with a professorial appointment in
Medical Genetics and Microbiology. In 2005 he
was awarded the Paul Marks Prize for Cancer
Research given by the Memorial Sloan-Kettering
Cancer Center. They (he and wife Liliana Attisano)
have published jointly on
the transforming growth factor-beta family of cell
signalling proteins that regulate cell growth and
function.
https://csmb-scbm.ca/uploads/CSBMCB_bulletin2007.pdf
Parents
Sign in to add mentor| Jaro Sodek | grad student | 1991 | University of Toronto (Chemistry Tree) | |
| (Regulation of connective tissue cells by transforming growth factor-b3.) | ||||
| Joan Massague | post-doc | (MathTree) | ||
Children
Sign in to add trainee| Yu (Sunny) Liu | grad student | ||
| Peter A. Kavsak | grad student | 2002 | University of Toronto |
| Teresa A. Reguly | grad student | 2003 | University of Toronto |
| Azadeh Golipour | grad student | 2013 | University of Toronto |
| Valbona Luga | grad student | 2013 | University of Toronto |
| Payman Samavarchi-Tehrani | grad student | 2013 | University of Toronto |
BETA: Related publications
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Publications
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| Ahmad S, Christova T, Pye M, et al. (2025) Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway. Cells. 14 |
| Fink M, Njah K, Patel SJ, et al. (2024) Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGFβ and Hippo signalling to drive regeneration. Nature Cell Biology |
| Yanchus C, Drucker KL, Kollmeyer TM, et al. (2022) A noncoding single-nucleotide polymorphism at 8q24 drives -mutant glioma formation. Science (New York, N.Y.). 378: 68-78 |
| Zhang T, He X, Caldwell L, et al. (2022) NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling. Science Translational Medicine. 14: eaaz4028 |
| Kagiwada S, Aramaki S, Wu G, et al. (2021) YAP creates epiblast responsiveness to inductive signals for germ cell fate. Development (Cambridge, England) |
| Pearson JD, Trcka D, Lu S, et al. (2021) Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods. Virology Journal. 18: 99 |
| Aynaud MM, Hernandez JJ, Barutcu S, et al. (2021) A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2. Nature Communications. 12: 1405 |
| Isho B, Abe KT, Zuo M, et al. (2020) Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Science Immunology. 5 |
| Labibi B, Bashkurov M, Wrana JL, et al. (2020) Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap. Iscience. 23: 101416 |
| Sivitilli AA, Gosio JT, Ghoshal B, et al. (2020) Robust production of uniform human cerebral organoids from pluripotent stem cells. Life Science Alliance. 3 |