Patricia Cortes
Affiliations: | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
Molecular Biology, Immunology, Cell BiologyGoogle:
"Patricia Cortes"Children
Sign in to add trainee| Jorge Mansilla-Soto | grad student | 2006 | Mount Sinai School of Medicine |
| Kelly L. West | grad student | 2006 | Mount Sinai School of Medicine |
| Shruti Malu | grad student | 2010 | Mount Sinai School of Medicine |
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Publications
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| Vu DD, Bonucci A, Brenière M, et al. (2024) Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro. Nature Structural & Molecular Biology |
| Vu DD, Bonucci A, Brenière M, et al. (2023) Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates . Biorxiv : the Preprint Server For Biology |
| Malashetty V, Au A, Chavez J, et al. (2023) The DNA binding domain and the C-terminal region of DNA Ligase IV specify its role in V(D)J recombination. Plos One. 18: e0282236 |
| Maffucci P, Chavez J, Jurkiw TJ, et al. (2018) Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies. The Journal of Clinical Investigation |
| Charlier C, Bouvignies G, Pelupessy P, et al. (2017) Structure and dynamics of an intrinsically disordered protein region that partially folds upon binding by chemical-exchange NMR. Journal of the American Chemical Society |
| Francis DB, Kozlov M, Chavez J, et al. (2014) DNA Ligase IV regulates XRCC4 nuclear localization. Dna Repair. 21: 36-42 |
| van Til NP, Sarwari R, Visser TP, et al. (2014) Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome. The Journal of Allergy and Clinical Immunology. 133: 1116-23 |
| De Ioannes P, Malu S, Cortes P, et al. (2012) Structural basis of DNA ligase IV-Artemis interaction in nonhomologous end-joining. Cell Reports. 2: 1505-12 |
| Malu S, Malshetty V, Francis D, et al. (2012) Role of non-homologous end joining in V(D)J recombination. Immunologic Research. 54: 233-46 |
| Malu S, De Ioannes P, Kozlov M, et al. (2012) Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. The Journal of Experimental Medicine. 209: 955-63 |