Leonidas C. Platanias
Affiliations: | Northwestern University, Evanston, IL |
Area:
Cell Biology, OncologyGoogle:
"Leonidas Platanias"Children
Sign in to add trainee| Nick Giafis | grad student | 2006 | Northwestern |
| Patrick Yoon | grad student | 2007 | Northwestern |
| Amanda J. Redig | grad student | 2009 | Northwestern |
| Sonali S. Joshi | grad student | 2011 | Northwestern |
| Bhumika Sharma | grad student | 2012 | Northwestern |
| Eliza Vakana | grad student | 2013 | Northwestern |
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Publications
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| Vagadia PP, Izquierdo-Ferrer J, Mazewski C, et al. (2025) Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia. Journal of Medicinal Chemistry. 68: 5824-5844 |
| Chen H, Bai Y, Kobayashi M, et al. (2023) PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation. Molecular Cancer Research : McR |
| Saleiro D, Kosciuczuk EM, Fischietti M, et al. (2023) Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells. Cancer Research Communications. 3: 943-951 |
| Mazewski C, Platanias LC. (2023) MNK Proteins as Therapeutic Targets in Leukemia. Oncotargets and Therapy. 16: 283-295 |
| Fenton SE, Zannikou M, Ilut L, et al. (2022) Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors. Molecular Cancer Research : McR |
| Fischietti M, Eckerdt F, Perez RE, et al. (2022) SLFN11 negatively regulates non-canonical NFkB signaling to promote glioblastoma progression. Cancer Research Communications. 2: 966-978 |
| Chen H, Bai Y, Kobayashi M, et al. (2022) PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. Blood |
| Perez RE, Saleiro D, Ilut L, et al. (2022) Regulation of IFNα-induced expression of the short ACE2 isoform by ULK1. Molecular Immunology. 147: 1-9 |
| Saleiro D, Wen JQ, Kosciuczuk EM, et al. (2022) Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms. Nature Communications. 13: 1750 |
| Suarez M, Blyth GT, Mina AA, et al. (2021) Inhibitory effects of Tomivosertib in acute myeloid leukemia. Oncotarget. 12: 955-966 |