Raymond F. Novak
Affiliations: | Molecular and Cellular Toxicology | Wayne State University, Detroit, MI, United States |
Area:
Cell Biology, Molecular BiologyGoogle:
"Raymond Novak"
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Publications
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| Shukla U, Tumma N, Gratsch T, et al. (2013) Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian target of rapamycin signaling in regulating miR-132/-212 and miR-122/-181a expression in primary cultured rat hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1769-77 |
| Rowlands JC, Budinsky R, Gollapudi B, et al. (2011) Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes. Chemosphere. 85: 232-8 |
| Zheng J, Hudder A, Zukowski K, et al. (2010) Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells. Cancer Letters. 296: 74-87 |
| Kim SK, Novak RF. (2007) The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression. Pharmacology & Therapeutics. 113: 88-120 |
| Kim SK, Abdelmegeed MA, Novak RF. (2006) The mitogen-activated protein kinase kinase (mek) inhibitor PD98059 elevates primary cultured rat hepatocyte glutathione levels independent of inhibiting mek. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 683-9 |
| Kim SK, Abdelmegeed MA, Novak RF. (2006) Identification of the insulin signaling cascade in the regulation of alpha-class glutathione S-transferase expression in primary cultured rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 316: 1255-61 |
| Kim SK, Woodcroft KJ, Oh SJ, et al. (2005) Role of mechanical and redox stress in activation of mitogen-activated protein kinases in primary cultured rat hepatocytes. Biochemical Pharmacology. 70: 1785-95 |
| Abdelmegeed MA, Carruthers NJ, Woodcroft KJ, et al. (2005) Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 315: 203-13 |
| Kim SK, Woodcroft KJ, Khodadadeh SS, et al. (2004) Insulin signaling regulates gamma-glutamylcysteine ligase catalytic subunit expression in primary cultured rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 311: 99-108 |
| Abdelmegeed MA, Kim SK, Woodcroft KJ, et al. (2004) Acetoacetate activation of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in primary cultured rat hepatocytes: role of oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. 310: 728-36 |