Leonard C. Erickson

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Pharmacology, Molecular Biology
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"Leonard Erickson"
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Publications

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Cornetta K, Croop J, Dropcho E, et al. (2006) A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase. Cancer Gene Therapy. 13: 886-95
Zhang Q, Ohannesian DW, Erickson LC. (2004) Hammerhead ribozyme-mediated sensitization of human tumor cells after treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea. The Journal of Pharmacology and Experimental Therapeutics. 309: 506-14
Kreklau EL, Pollok KE, Bailey BJ, et al. (2003) Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea. Molecular Cancer Therapeutics. 2: 1321-9
Hirose Y, Kreklau EL, Erickson LC, et al. (2003) Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity. Journal of Neurosurgery. 98: 591-8
Zheng QH, Liu X, Fei X, et al. (2002) Synthesis of radiolabeled O6-benzylguanine derivatives as new potential PET tumor imaging agents for the DNA repair protein O6-alkylguanine-DNA alkyltransferase Journal of Labelled Compounds and Radiopharmaceuticals. 45: 1239-1252
Kreklau EL, Limp-Foster M, Liu N, et al. (2001) A novel fluorometric oligonucleotide assay to measure O( 6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase. Nucleic Acids Research. 29: 2558-66
Zhang Q, Ohannesian DW, Kreklau EL, et al. (2001) Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA. The Journal of Pharmacology and Experimental Therapeutics. 298: 141-7
Santiago LR, Erickson LC, Hanin I. (1998) AF64A-induced changes in N-myc expression in the LA-N-2 human neuroblastoma cell line are modulated by choline and hemicholinium-3. Neurochemical Research. 23: 743-50
Santiago LR, Ivy MT, Erickson LC, et al. (1995) AF64A-induced cytotoxicity and changes in choline acetyltransferase activity in the LA-N-2 neuroblastoma cell line are modulated by choline and hemicholinium-3. Journal of Neuroscience Methods. 61: 185-90
Kroes RA, Erickson LC. (1995) The role of mRNA stability and transcription in O6-methylguanine DNA methyltransferase (MGMT) expression in Mer+ human tumor cells. Carcinogenesis. 16: 2255-7
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