Thomas J. Begley
Affiliations: | Biomedical Sciences | State University of New York, Albany, Albany, NY, United States |
Area:
Molecular Biology, Cell Biology, Genetics, OncologyGoogle:
"Thomas Begley"
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Publications
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Mitchener MM, Begley TJ, Dedon PC. (2023) Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins. Accounts of Chemical Research. 56: 3504-3514 |
Dedon PC, Begley TJ. (2022) Dysfunctional tRNA reprogramming and codon-biased translation in cancer. Trends in Molecular Medicine. 28: 964-978 |
Huber SM, Begley U, Sarkar A, et al. (2022) Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123529119 |
Evke S, Lin Q, Melendez JA, et al. (2022) Epitranscriptomic Reprogramming Is Required to Prevent Stress and Damage from Acetaminophen. Genes. 13 |
St John N, Freedland J, Baldino H, et al. (2020) Genome Profiling for Aflatoxin B Resistance in Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B-Associated DNA Damage. G3 (Bethesda, Md.) |
Leonardi A, Kovalchuk N, Yin L, et al. (2020) The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene. Epigenetics. 1-18 |
Pollo-Oliveira L, Klassen R, Davis N, et al. (2020) Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. Biomolecules. 10 |
Lee MY, Leonardi A, Begley TJ, et al. (2019) Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming. Redox Biology. 28: 101375 |
Leonardi A, Evke S, Lee M, et al. (2019) Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins. Free Radical Biology & Medicine |
Huber SM, Leonardi A, Dedon PC, et al. (2019) The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress. Toxics. 7 |