Diane C. Fingar

Affiliations: 
Cell and Developmental Biology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Cell Biology
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"Diane Fingar"
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Publications

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Kazyken D, Lentz SI, Wadley M, et al. (2023) Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation. The Journal of Biological Chemistry. 299: 105097
Bodur C, Kazyken D, Huang K, et al. (2022) TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance. Diabetes
Tooley AS, Kazyken D, Bodur C, et al. (2021) The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt. The Journal of Biological Chemistry. 297: 100942
Losiewicz MK, Elghazi L, Fingar DC, et al. (2020) mTORC1 and mTORC2 expression in inner retinal neurons and glial cells. Experimental Eye Research. 108131
Kowalsky AH, Namkoong S, Mettetal E, et al. (2020) The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation. The Journal of Biological Chemistry
Kazyken D, Magnuson B, Bodur C, et al. (2019) AMPK directly activates mTORC2 to promote cell survival during acute energetic stress. Science Signaling. 12
Walker NM, Mazzoni SM, Vittal R, et al. (2018) c-Jun N-terminal kinase (JNK)-mediated induction of mSin1 expression and mTORC2 activation in mesenchymal cells during fibrosis. The Journal of Biological Chemistry
Bodur C, Kazyken D, Huang K, et al. (2017) The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. The Embo Journal
Walker NM, Belloli EA, Stuckey L, et al. (2016) Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation. The Journal of Biological Chemistry
Fingar DC. (2015) Rag Ubiquitination Recruits a GATOR1: Attenuation of Amino Acid-Induced mTORC1 Signaling. Molecular Cell. 58: 713-5
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