Kristina B. Kruse, Ph.D.

Affiliations: 
2005 University of Nevada, Reno, Reno, NV, United States 
Area:
Cell Biology, Molecular Biology
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"Kristina Kruse"

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Ardythe A. McCracken grad student 2005 University of Nevada, Reno
 (ER quality control beyond ERAD and the UPR: Uncovering the role of autophagy.)
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Publications

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Scott CM, Kruse KB, Schmidt BZ, et al. (2007) ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly. Molecular Biology of the Cell. 18: 3776-87
Kruse KB, Brodsky JL, McCracken AA. (2006) Autophagy: an ER protein quality control process. Autophagy. 2: 135-7
Kruse KB, Dear A, Kaltenbrun ER, et al. (2006) Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: an explanation for liver disease. The American Journal of Pathology. 168: 1299-308; quiz 1404-
Kruse KB, Brodsky JL, McCracken AA. (2006) Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. Molecular Biology of the Cell. 17: 203-12
Palmer EA, Kruse KB, Fewell SW, et al. (2003) Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation. Journal of Cell Science. 116: 2361-73
Palmer EA, Kruse KB, McCracken AA. (2001) A yeast expression vector and leucine selection in Escherichia coli to aid in the identification of novel genes Plasmid. 46: 57-59
McCracken AA, Werner ED, Powell MJ, et al. (2000) Differential fates of invertase mutants in the yeast endoplasmic reticulum. Yeast (Chichester, England). 16: 49-55
Brodsky JL, Werner ED, Dubas ME, et al. (1999) The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct. The Journal of Biological Chemistry. 274: 3453-60
McCracken AA, Kruse KB. (1993) Selective protein degradation in the yeast exocytic pathway. Molecular Biology of the Cell. 4: 729-36
McCracken AA, Kruse KB, Valentine J, et al. (1991) Construction and expression of alpha 1-proteinase inhibitor mutants and the effects of these mutations on secretion of the variant inhibitors. The Journal of Biological Chemistry. 266: 7578-82
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