Brendan D. Looyenga, Ph.D.

Affiliations: 
2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular Biology, Cell Biology, Physiology Biology
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"Brendan Looyenga"

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Gary D. Hammer grad student 2006 University of Michigan
 (Mechanisms of tumorigenesis in the inhibin-null mouse: An analysis of dysregulated TGF-beta family signaling in steroidogenic organs.)
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Publications

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Rosette KA, Lander SM, VanOpstall C, et al. (2021) Three-dimensional coculture provides an improved in vitro model for papillary renal cell carcinoma. American Journal of Physiology. Renal Physiology. 321: F33-F46
Lodge EK, Bell JD, Roloff EM, et al. (2020) Pharmacologic inhibition of N-linked glycan trimming with kifunensine disrupts GLUT1 trafficking and glucose uptake. Biochimie
Rylaarsdam LE, Johnecheck GN, Looyenga BD, et al. (2019) GLUT1 is associated with sphingolipid-organized, cholesterol-independent domains in L929 mouse fibroblast cells. Biochimie
Lanning NJ, VanOpstall C, Goodall ML, et al. (2018) LRRK2 Deficiency Impairs trans-Golgi to Lysosome Trafficking and Endocytic Cargo Degradation in Human Renal Proximal Tubule Epithelial Cells. American Journal of Physiology. Renal Physiology
Looyenga B, VanOpstall C, Lee Z, et al. (2016) Determination of GLUT1 Oligomerization Parameters using Bioluminescent Förster Resonance Energy Transfer. Scientific Reports. 6: 29130
Looyenga BD, Resau J, MacKeigan JP. (2013) Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway. Plos One. 8: e66548
Looyenga BD, Mackeigan JP. (2012) Characterization of differential protein tethering at the plasma membrane in response to epidermal growth factor signaling. Journal of Proteome Research. 11: 3101-11
Looyenga BD, Hutchings D, Cherni I, et al. (2012) STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma. Plos One. 7: e30820
Looyenga BD. (2012) Abstract 168: Cytokine signaling through the JAK2/STAT3 pathway is a viable therapeutic target in non-small cell lung cancer Cancer Research. 72: 168-168
Ding Y, Huang D, Zhang Z, et al. (2011) Combined gene expression profiling and RNAi screening in clear cell renal cell carcinoma identify PLK1 and other therapeutic kinase targets. Cancer Research. 71: 5225-34
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