Zamaneh Kassiri, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Animal Physiology Biology, Cell Biology
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"Zamaneh Kassiri"

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Peter H. Backx grad student 2002 University of Toronto
 (Reduction of transient outward potassium current and hypertrophy in neonatal rat ventricular myocytes: Role of calcium-dependent signaling pathways.)
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Publications

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Aujla PK, Hu M, Hartley B, et al. (2022) Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway. Hypertension (Dallas, Tex. : 1979)
Nagalingam RS, Chattopadhyaya S, Al-Hattab DS, et al. (2022) Scleraxis and fibrosis in the pressure-overloaded heart. European Heart Journal
Chute M, Aujla PK, Li Y, et al. (2022) ADAM15 is required for optimal collagen cross-linking and scar formation following myocardial infarction. Matrix Biology : Journal of the International Society For Matrix Biology
Fan D, Kassiri Z. (2021) Modulation of Cardiac Fibrosis in and Beyond Cells. Frontiers in Molecular Biosciences. 8: 750626
Jana S, Aujla P, Hu M, et al. (2021) Gelsolin is an important mediator of Angiotensin II-induced activation of cardiac fibroblasts and fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21932
Oh Y, Yang S, Liu X, et al. (2020) Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice. Frontiers in Physiology. 11: 605671
Patel VB, Zhabyeyev P, Chen X, et al. (2018) PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease. Nature Communications. 9: 5390
Chen X, Zhabyeyev P, Azad AK, et al. (2018) Endothelial and Cardiomyocyte PI3Kβ Divergently Regulate Cardiac Remodeling in Response to Ischemic Injury. Cardiovascular Research
Wang W, Patel VB, Parajuli N, et al. (2014) Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease. Journal of Molecular Medicine (Berlin, Germany). 92: 847-58
Fan D, Takawale A, Basu R, et al. (2014) Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction. Cardiovascular Research. 103: 268-80
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