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Diana Ronai, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Immunology
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"Diana Ronai"
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Marc J. Shulman grad student 2002 University of Toronto
 (Epigenetic regulation of immunoglobulin heavy -chain gene expression.)

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Publications

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Chi C, Ronai D, Than MT, et al. (2016) Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans. Genes & Development. 30: 307-20
Parsa JY, Ramachandran S, Zaheen A, et al. (2012) Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis. Plos Genetics. 8: e1002518
Li Z, Luo Z, Ronai D, et al. (2007) Targeting AID to the Ig genes. Advances in Experimental Medicine and Biology. 596: 93-109
Ronai D, Iglesias-Ussel MD, Fan M, et al. (2007) Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. The Journal of Experimental Medicine. 204: 181-90
Li Z, Peled JU, Zhao C, et al. (2006) A role for Mlh3 in somatic hypermutation. Dna Repair. 5: 675-82
Ronai D, Iglesias-Ussel MD, Fan M, et al. (2005) Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 11829-34
Luo Z, Ronai D, Scharff MD. (2004) The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies. The Journal of Allergy and Clinical Immunology. 114: 726-35; quiz 736
Li Z, Scherer SJ, Ronai D, et al. (2004) Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. The Journal of Experimental Medicine. 200: 47-59
Ronai D, Berru M, Shulman MJ. (2004) The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. Genetics. 167: 411-21
Li Z, Woo CJ, Iglesias-Ussel MD, et al. (2004) The generation of antibody diversity through somatic hypermutation and class switch recombination. Genes & Development. 18: 1-11
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