Natasha C. Lucki, Ph.D.

Affiliations: 
2011 Georgia Institute of Technology, Atlanta, GA 
Area:
Molecular Biology, Cell Biology, Endocrinology Biology
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"Natasha Lucki"

Parents

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Marion B. Sewer grad student 2011 Georgia Tech
 (Characterization of the role of acid ceramidase in adrenocortical steroid hormone biosynthesis.)
Luke L. Lairson post-doc Calibr (Chemistry Tree)
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Publications

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Lucki NC, Villa GR, Vergani N, et al. (2019) A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America
Mullarky E, Lucki NC, Beheshti Zavareh R, et al. (2016) Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers. Proceedings of the National Academy of Sciences of the United States of America
Cai K, Lucki NC, Sewer MB. (2014) Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells. Biochimica Et Biophysica Acta. 1841: 552-62
Li D, Dammer EB, Lucki NC, et al. (2013) cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells. Molecular Biology of the Cell. 24: 848-57
Lucki NC, Li D, Bandyopadhyay S, et al. (2012) Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. Molecular and Cellular Biology. 32: 4419-31
Lucki NC, Bandyopadhyay S, Wang E, et al. (2012) Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Molecular Endocrinology (Baltimore, Md.). 26: 228-43
Lucki NC, Sewer MB. (2012) Nuclear sphingolipid metabolism. Annual Review of Physiology. 74: 131-51
Lucki NC, Li D, Sewer MB. (2012) Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells. Molecular and Cellular Endocrinology. 348: 165-75
Lucki NC, Sewer MB. (2011) Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression. The Journal of Biological Chemistry. 286: 19399-409
Lucki NC, Sewer MB. (2010) The interplay between bioactive sphingolipids and steroid hormones. Steroids. 75: 390-9
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