Brian N. Wroble, Ph.D.

Affiliations: 
2005 Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
Cell Biology
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"Brian Wroble"

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Jill C. Sible grad student 2005 Virginia Tech
 (The role of Chk2 and Wee1 protein kinases during the early embryonic development of Xenopus laevis.)
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Publications

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Peixoto PM, Lue JK, Ryu SY, et al. (2011) Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect. The American Journal of Pathology. 178: 48-54
Sible JC, Wroble BN. (2009) Expression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation. Methods in Molecular Biology (Clifton, N.J.). 518: 1-15
Adjerid N, Wroble BN, Sible JC. (2008) Chk1 is activated at the midblastula transition in Xenopus laevis embryos independently of DNA content and the cyclin E/Cdk2 developmental timer. Cell Cycle (Georgetown, Tex.). 7: 1112-6
Wroble BN, Finkielstein CV, Sible JC. (2007) Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis. Bmc Developmental Biology. 7: 119
Carter AD, Wroble BN, Sible JC. (2006) Cyclin A1/Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryos. Cell Cycle (Georgetown, Tex.). 5: 2230-6
Wroble BN, Sible JC. (2005) Chk2/Cds1 protein kinase blocks apoptosis during early development of Xenopus laevis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 1359-65
Petrus MJ, Wilhelm DE, Murakami M, et al. (2004) Altered expression of Chk1 disrupts cell cycle remodeling at the midblastula transition in Xenopus laevis embryos. Cell Cycle (Georgetown, Tex.). 3: 212-7
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