Despina Komninou, Ph.D.

Affiliations: 
2000 New York Medical College, New York, NY, United States 
Area:
Pathology
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"Despina Komninou"

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John P. Richie grad student 2000 New York Medical College
 (Oxidative stress and aging in colon carcinogenesis.)
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Publications

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Komninou D, Malloy VL, Zimmerman JA, et al. (2019) Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats. Geroscience
Bartels LE, Mattheolabakis G, Vaeth BM, et al. (2016) The novel agent phospho-glycerol-ibuprofen-amide (MDC-330) inhibits glioblastoma growth in mice: an effect mediated by cyclin D1. Carcinogenesis
Huang L, Mackenzie GG, Sun Y, et al. (2011) Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds. Cancer Research. 71: 7617-27
Mackenzie GG, Ouyang N, Xie G, et al. (2011) Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice. Cancer Prevention Research (Philadelphia, Pa.). 4: 1052-60
Xie G, Sun Y, Nie T, et al. (2011) Phospho-ibuprofen (MDC-917) is a novel agent against colon cancer: efficacy, metabolism, and pharmacokinetics in mouse models. The Journal of Pharmacology and Experimental Therapeutics. 337: 876-86
Huang L, Zhu C, Sun Y, et al. (2010) Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effect. Carcinogenesis. 31: 1982-90
Mackenzie GG, Sun Y, Huang L, et al. (2010) Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice. Gastroenterology. 139: 1320-32
Richie JP, Komninou D, Albino AP. (2007) Induction of colon tumorigenesis by glutathione depletion in p53-knock-out mice. International Journal of Oncology. 30: 1539-43
Huang Z, Komninou D, Kleinman W, et al. (2007) Enhanced levels of glutathione and protein glutathiolation in rat tongue epithelium during 4-NQO-induced carcinogenesis. International Journal of Cancer. 120: 1396-401
Komninou D, Leutzinger Y, Reddy BS, et al. (2006) Methionine restriction inhibits colon carcinogenesis. Nutrition and Cancer. 54: 202-8
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