Travis L. Schmit, Ph.D.

Affiliations: 
2010 University of Wisconsin, Madison, Madison, WI 
Area:
Oncology, Cell Biology
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"Travis Schmit"

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Nihal Ahmad grad student 2010 UW Madison
 (Regulation of polo-like kinase 1 by Numb during the melanoma cell cycle.)
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Publications

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Schmit TL, Nihal M, Ndiaye M, et al. (2012) Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis. Cancer Research. 72: 3864-72
Wilhelm M, Kukekov NV, Schmit TL, et al. (2012) Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. The Journal of Biological Chemistry. 287: 2247-56
Nihal M, Stutz N, Schmit T, et al. (2011) Polo-like kinase 1 (Plk1) is expressed by cutaneous T-cell lymphomas (CTCLs), and its downregulation promotes cell cycle arrest and apoptosis. Cell Cycle (Georgetown, Tex.). 10: 1303-11
Jung-Hynes B, Schmit TL, Reagan-Shaw SR, et al. (2011) Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model. Journal of Pineal Research. 50: 140-9
Ledesma MC, Jung-Hynes B, Schmit TL, et al. (2011) Selenium and vitamin E for prostate cancer: post-SELECT (Selenium and Vitamin E Cancer Prevention Trial) status. Molecular Medicine (Cambridge, Mass.). 17: 134-43
Schmit TL, Ledesma MC, Ahmad N. (2010) Modulating polo-like kinase 1 as a means for cancer chemoprevention. Pharmaceutical Research. 27: 989-98
Jung-Hynes BD, Schmit TL, Reagan-Shaw S, et al. (2010) Abstract 5478: Melatonin, a novel Sirt1 inhibitor, imparts anti-proliferative effects against PCain vitroin cell culture andin vivoin transgenic adenocarcinoma of mouse prostate (TRAMP) model Cancer Research. 70: 5478-5478
Schmit TL, Setaluri V, Spiegelman VS, et al. (2010) Abstract 1064: Numb, a progenitor cell fate determinant and intrinsic inhibitor of Notch signaling, is cell cycle regulated and required for proper mitotic entry and progression in melanoma cells Cellular and Molecular Biology. 70: 1064-1064
Schmit TL, Setaluri V, Spiegelman VS, et al. (2010) Abstract 1062: Numb, an intrinsic Notch inhibitor, possesses a tumor suppressor role through regulation of Plk1 localization during mitosis Cancer Research. 70: 1062-1062
Schmit TL, Zhong W, Nihal M, et al. (2009) Polo-like kinase 1 (Plk1) in non-melanoma skin cancers. Cell Cycle (Georgetown, Tex.). 8: 2697-702
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