Curtis J. Oleschuk, Ph.D.
Affiliations: | 2004 | Queen's University, Canada, Kingston, Ontario, Canada |
Area:
PharmacologyGoogle:
"Curtis Oleschuk"Parents
Sign in to add mentor| Susan P. C. Cole | grad student | 2004 | Queen's University, Canada | |
| (Structure-function studies of multidrug resistance proteins.) | ||||
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| Rosenberg MF, Oleschuk CJ, Wu P, et al. (2010) Structure of a human multidrug transporter in an inward-facing conformation. Journal of Structural Biology. 170: 540-7 |
| Wu P, Oleschuk CJ, Mao Q, et al. (2005) Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites. Molecular Pharmacology. 68: 1455-65 |
| Oleschuk CJ, Deeley RG, Cole SP. (2003) Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G280-9 |
| Koike K, Oleschuk CJ, Haimeur A, et al. (2002) Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. The Journal of Biological Chemistry. 277: 49495-503 |
| Ito K, Oleschuk CJ, Westlake C, et al. (2001) Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. The Journal of Biological Chemistry. 276: 38108-14 |
| Leslie EM, Mao Q, Oleschuk CJ, et al. (2001) Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Molecular Pharmacology. 59: 1171-80 |
| Loe DW, Oleschuk CJ, Deeley RG, et al. (2000) Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1. Biochemical and Biophysical Research Communications. 275: 795-803 |