Alexandria Lau, Ph.D.
Affiliations: | 2012 | Pharmacology & Toxicology | University of Arizona, Tucson, AZ |
Area:
Toxicology, Molecular Biology, Cell BiologyGoogle:
"Alexandria Lau"Parents
Sign in to add mentor| Donna D. Zhang | grad student | 2012 | University of Arizona | |
| (The role of the Nrf2-Keap1 pathway in autophagy and how it contributes to arsenic carcinogenicity.) | ||||
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Publications
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| Wu T, Wang XJ, Tian W, et al. (2014) Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. Free Radical Biology & Medicine. 67: 69-80 |
| Villeneuve NF, Tian W, Wu T, et al. (2013) USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Molecular Cell. 51: 68-79 |
| Lau A, Zheng Y, Tao S, et al. (2013) Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. Molecular and Cellular Biology. 33: 2436-46 |
| Tao S, Zheng Y, Lau A, et al. (2013) Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxidants & Redox Signaling. 19: 1647-61 |
| Lau A, Whitman SA, Jaramillo MC, et al. (2013) Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. Journal of Biochemical and Molecular Toxicology. 27: 99-105 |
| Lau A, Tian W, Whitman SA, et al. (2013) The predicted molecular weight of Nrf2: it is what it is not. Antioxidants & Redox Signaling. 18: 91-3 |
| Bray K, Mathew R, Lau A, et al. (2012) Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. Plos One. 7: e41831 |
| Chen W, Jiang T, Wang H, et al. (2012) Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxidants & Redox Signaling. 17: 1670-5 |
| Bray K, Mathew R, Lau A, et al. (2012) Cell death induced by autophagy and mTOR inhibition is RIPK-dependent necroptosis. Plos One |
| Sun Z, Wu T, Zhao F, et al. (2011) KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Molecular and Cellular Biology. 31: 1800-11 |