Marion R. Zillhardt, Ph.D.

Affiliations: 
2011 Cancer Biology University of Chicago, Chicago, IL 
Area:
Cell Biology, Oncology
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"Marion Zillhardt"

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Ernst Lengyel grad student 2011 Chicago
 (Stromal-mediated activation of c-MET in ovarian cancer metastasis: Opportunities for therapy.)
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Publications

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Mitra AK, Zillhardt M, Hua Y, et al. (2012) MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discovery. 2: 1100-8
Boyerinas B, Park SM, Murmann AE, et al. (2012) Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1. International Journal of Cancer. 130: 1787-97
Zillhardt M, Lengyel E. (2012) Abstract 48: Activation of c-Met receptor signaling by carcinoma-associated fibroblasts in the tumor microenvironment Cancer Research. 72: 48-48
Mitra AK, Zillhardt M, Hua Y, et al. (2012) Abstract 1481: microRNA mediated reprograming of fibroblasts into cancer associated fibroblasts in ovarian cancer Cancer Research. 72: 1481-1481
Nieman KM, Kenny HA, Penicka CV, et al. (2011) Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nature Medicine. 17: 1498-503
Zillhardt M, Park SM, Romero IL, et al. (2011) Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4042-51
Zillhardt M, Christensen JG, Lengyel E. (2010) An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis. Neoplasia (New York, N.Y.). 12: 1-10
Kaur S, Kenny HA, Jagadeeswaran S, et al. (2009) {beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer. The American Journal of Pathology. 175: 2184-96
Kenny HA, Dogan S, Zillhardt M, et al. (2009) Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis. Cancer Treatment and Research. 149: 335-51
Schiller KR, Zillhardt MR, Alley J, et al. (2009) Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model. Bmc Cancer. 9: 45
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