Valerie P. Zediak, Ph.D.

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Cell Biology
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"Valerie Zediak"

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Avinash Bhandoola grad student 2008 Penn
 (Aging and T cell development: Role of the hematopoietic stem cell and downstream T progenitors in bone marrow and thymus.)
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Publications

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Zediak VP, Wherry EJ, Berger SL. (2011) The contribution of epigenetic memory to immunologic memory. Current Opinion in Genetics & Development. 21: 154-9
Zediak VP, Johnnidis JB, Wherry EJ, et al. (2011) Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. Journal of Immunology (Baltimore, Md. : 1950). 186: 2705-9
Sambandam A, Bell JJ, Schwarz BA, et al. (2008) Progenitor migration to the thymus and T cell lineage commitment. Immunologic Research. 42: 65-74
Ruzankina Y, Pinzon-Guzman C, Asare A, et al. (2007) Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell. 1: 113-26
Zediak VP, Maillard I, Bhandoola A. (2007) Multiple prethymic defects underlie age-related loss of T progenitor competence. Blood. 110: 1161-7
Chen M, Kundu M, Shelat S, et al. (2007) Animal Model of Mitochondrial Dysfunction Generating Macrocytic Anemia and Myelodysplastic Bone Marrow Failure. Blood. 110: 402-402
Thompson J, Shelat S, Kujoth G, et al. (2007) C017 Animal model of mitochondrial dysfunction generating macrocytic anemia and myelodysplastic bone marrow failure Leukemia Research. 31: S31-S32
Zediak VP, Maillard I, Bhandoola A. (2005) Closer to the source: notch and the nature of thymus-settling cells. Immunity. 23: 245-8
Zediak VP, Bhandoola A. (2005) Aging and T cell development: interplay between progenitors and their environment. Seminars in Immunology. 17: 337-46
Sambandam A, Maillard I, Zediak VP, et al. (2005) Notch signaling controls the generation and differentiation of early T lineage progenitors. Nature Immunology. 6: 663-70
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