Shaun M. Goodyear, Ph.D.

Affiliations: 
2010 Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology
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"Shaun Goodyear"

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Mark E. Stearns grad student 2010 Drexel Medical School
 (Transforming growth factor beta and oncogenes c-myc and Bmi-1 contribute to the malignant transformation of intermediary basal epithelial cells of the prostate.)
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Publications

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Goodyear S, Brinster R. (2017) Isolation of the Spermatogonial Stem Cell-Containing Fraction from Testes. Cold Spring Harbor Protocols. 2017: pdb.prot094185
Niu Z, Goodyear SM, Avarbock MR, et al. (2016) Chemokine (C-X-C) Ligand 12 Facilitates Trafficking of Donor Spermatogonial Stem Cells. Stem Cells International. 2016: 5796305
Ngamcherdtrakul W, Morry J, Gu S, et al. (2015) Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer. Advanced Functional Materials. 25: 2646-2659
Goodyear SM. (2014) Abstract 5416: Development of a nanoparticle platform for the targeted delivery of siRNA to HER2-positive breast cancers Cancer Research. 74: 5416-5416
Amatangelo MD, Goodyear S, Varma D, et al. (2012) c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial-mesenchymal transition and invasion in prostate cancer. Carcinogenesis. 33: 1965-75
Wu X, Goodyear SM, Abramowitz LK, et al. (2012) Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years. Human Reproduction (Oxford, England). 27: 1249-59
Wu X, Goodyear SM, Tobias JW, et al. (2011) Spermatogonial stem cell self-renewal requires ETV5-mediated downstream activation of Brachyury in mice. Biology of Reproduction. 85: 1114-23
Kubota H, Wu X, Goodyear SM, et al. (2011) Glial cell line-derived neurotrophic factor and endothelial cells promote self-renewal of rabbit germ cells with spermatogonial stem cell properties. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2604-14
Stearns ME, Amatangelo MD, Varma D, et al. (2010) Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice. The American Journal of Pathology. 177: 3169-79
Goodyear SM, Kheyfets SB, Garcia FU, et al. (2009) Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines. The Prostate. 69: 982-90
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