Alexandre Patenaude, Ph.D.

Affiliations: 
2005 Universite Laval (Canada) 
Area:
Molecular Biology
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"Alexandre Patenaude"

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Marc-Edouard Mirault grad student 2005 Universite Laval (Canada)
 (Thioredoxine reductase mitochondriale: Etude de son role dans l'apoptose, le redox et la croissance cellulaires.)
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Publications

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Hawkins RFW, Patenaude A, Dumas A, et al. (2017) ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell-dependent autoimmune encephalomyelitis. Jci Insight. 2
Patenaude A, Fuller M, Chang L, et al. (2014) Endothelial-specific Notch blockade inhibits vascular function and tumor growth through an eNOS-dependent mechanism. Cancer Research. 74: 2402-11
Chang AC, Patenaude A, Lu K, et al. (2013) Notch-dependent regulation of the ischemic vasodilatory response--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 510-2
Chang L, Noseda M, Higginson M, et al. (2012) Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 6993-8
Patenaude A, Chang L, Diaz E, et al. (2011) Abstract 3476: Blockade of endothelial Notch diminishes tumor growth and perfusion Cancer Research. 71: 3476-3476
Patenaude A, Fortin JS, Deschenes R, et al. (2010) Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation. Canadian Journal of Physiology and Pharmacology. 88: 1102-14
Fortin J, Patenaude A, Deschesnes RG, et al. (2010) ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, SociéTé Canadienne Des Sciences Pharmaceutiques. 13: 175-90
Patenaude A, Parker J, Karsan A. (2010) Involvement of endothelial progenitor cells in tumor vascularization. Microvascular Research. 79: 217-23
Fortin JS, Côté MF, Lacroix J, et al. (2008) Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation. Bioorganic & Medicinal Chemistry Letters. 18: 3526-31
Moreau E, Fortin S, Lacroix J, et al. (2008) N-Phenyl-N'-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: role of carbonyl groups in the covalent binding to the colchicine-binding site. Bioorganic & Medicinal Chemistry. 16: 1206-17
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